As per the current market research conducted by CMI Team, the global Gene Synthesis market is expected to record a CAGR of 19% from 2023 to 2032. In 2022, the market size is projected to reach a valuation of USD 1,200 million. By 2032, the valuation is anticipated to reach USD 5,879 million.

Gene Synthesis Market: Growth Factors and Dynamics

The gene synthesis market has been experiencing significant growth dynamics in recent years. Gene synthesis, also known as DNA synthesis or gene engineering, involves the artificial production of DNA sequences. It plays a crucial role in various fields, including biotechnology, pharmaceuticals, academic research, and agriculture.

Here are some key growth dynamics driving the gene synthesis market:

  • Advancements in DNA sequencing and synthesis technologies: The development of high-throughput DNA sequencing techniques and cost-effective gene synthesis methods has revolutionized the field. Next-generation sequencing platforms and novel gene synthesis technologies have made it faster, more accurate, and more affordable to synthesize genes, thereby driving market growth.
  • Increasing applications in research and development: Gene synthesis is widely utilized in research and development activities across multiple sectors. It enables scientists to study and manipulate specific genes, understand their functions, and develop new products and therapies. The growing demand for personalized medicine, synthetic biology, and genetic engineering has fueled the demand for gene synthesis services.
  • Rising adoption of synthetic biology: Synthetic biology, which involves designing and constructing new biological parts, devices, and systems, has gained immense popularity. Gene synthesis is a critical component of synthetic biology as it enables the creation of artificial DNA sequences for engineering new organisms or biological systems. The expanding applications of synthetic biology have boosted the demand for gene synthesis.
  • Increasing investments and funding: The gene synthesis market has attracted significant public and private investments. Governments, academic institutions, and biotechnology companies are investing heavily in gene synthesis technologies and infrastructure. The availability of funding and research grants has facilitated technological advancements and product development, further driving market growth.
  • Growing demand for custom-made DNA constructs: The ability to custom-design DNA sequences has become increasingly important in various industries. Researchers and biotech companies require customized DNA constructs for applications such as gene therapy, vaccine development, enzyme engineering, and biofuel production. Gene synthesis offers a flexible and efficient solution to obtain desired DNA sequences, contributing to market growth.
  • Increasing outsourcing of gene synthesis services: Many academic and research institutions and small biotech firms are outsourcing gene synthesis services to specialized companies. Outsourcing allows them to access advanced technologies, expertise, and cost-effective solutions. This trend has created opportunities for gene synthesis service providers, driving market expansion.
  • Regulatory support and ethical considerations: Governments and regulatory bodies have recognized the potential of gene synthesis in advancing scientific research and innovation. They are working to create supportive regulatory frameworks to ensure synthetic DNA’s safety, quality, and ethical use. This regulatory support has instilled confidence in the market and encouraged its growth.

Report Scope

Feature of the ReportDetails
Market Size in 2023USD 1667.9 Million
Projected Market Size in 2032USD 5,879 Million
Market Size in 2022USD 1,200 Million
CAGR Growth Rate19% CAGR
Base Year2023
Forecast Period2024-2033
Key SegmentBy Method, Services, Application, End-use and Region
Report CoverageRevenue Estimation and Forecast, Company Profile, Competitive Landscape, Growth Factors and Recent Trends
Regional ScopeNorth America, Europe, Asia Pacific, Middle East & Africa, and South & Central America
Buying OptionsRequest tailored purchasing options to fulfil your requirements for research.

Gene Synthesis Market: COVID-19 Analysis

The COVID-19 pandemic has had both positive and negative impacts on the gene synthesis market. Here’s an analysis of how the market has been affected:

Positive Impacts:

  • Increased focus on vaccine development: The urgent need for effective vaccines against COVID-19 led to a significant surge in vaccine development efforts. Gene synthesis played a crucial role in the rapid development of mRNA-based vaccines, such as the Pfizer-BioNTech and Moderna vaccines. This accelerated the adoption of gene synthesis technologies and services, driving market growth.

Negative Impacts:

  • Disruption of supply chains: The global lockdowns, travel restrictions, and disruptions in international logistics negatively impacted the supply chains of gene synthesis companies. Delays in the delivery of reagents, enzymes, and other essential materials hampered the efficiency of gene synthesis operations. This led to project delays and affected the overall market growth.
  • Temporary closure of research institutions: Many academic institutions and research laboratories had to temporarily close or reduce their operations during the pandemic. This resulted in a slowdown of research activities, including those involving gene synthesis. The reduced demand for gene synthesis services from these institutions had a negative impact on the market.

Global Gene Synthesis Market 2023–2032 (By Million)

List of the prominent players in the Gene Synthesis Market:

  • GenScript
  • Brooks Automation Inc. (GENEWIZ)
  • Boster Biological Technology
  • Twist Bioscience
  • ProteoGenix Inc
  • Biomatik
  • ProMab Biotechnologies Inc.
  • Thermo Fisher Scientific Inc.
  • Integrated DNA Technologies Inc.
  • OriGene Technologies Inc.
  • Others

The Gene Synthesis Market is segmented as follows:

By Method

  • Solid-phase Synthesis
  • Chip-based Synthesis
  • PCR-based Enzyme Synthesis

By Services

  • Antibody DNA Synthesis
  • Viral DNA Synthesis
  • Others

By Application

  • Gene & Cell Therapy Development
  • Vaccine Development
  • Disease Diagnosis
  • Others

By End-use

  • Biotechnology & Pharmaceutical Companies
  • Academic & Government Research Institutes
  • Contract Research Organizations

By Region

North America

  • The U.S.
  • Canada
  • Mexico


  • France
  • The UK
  • Spain
  • Germany
  • Italy
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of Asia Pacific

The Middle East & Africa

  • Saudi Arabia
  • UAE
  • Egypt
  • Kuwait
  • South Africa
  • Rest of the Middle East & Africa

Latin America

  • Brazil
  • Argentina
  • Rest of Latin America