As per the current market research conducted by the CMI Team, the global NSCLC Drug Market size is expected to record a CAGR of 8.1% from 2024 to 2033. In 2024, the market size is projected to reach a valuation of USD 34,175.6 Million. By 2033, the valuation is anticipated to reach USD 68,888.6 Million.

NSCLC Drug Market: Growth Factors and Dynamics

  • Advancements in Targeted Therapies: The NSCLC drug market is driven by advancements in targeted therapies, such as tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs), which offer improved efficacy and tolerability compared to traditional chemotherapy.
  • Increasing Incidence of NSCLC: The rising prevalence of NSCLC, attributed to factors such as smoking, air pollution, and aging populations, drive market growth by increasing the demand for effective treatment options and supportive care interventions.
  • Personalized Medicine Approaches: Growing adoption of personalized medicine approaches, including biomarker testing and genetic profiling, allows for the identification of specific molecular targets and the development of tailored treatment regimens, enhancing therapeutic outcomes and driving market expansion.
  • Clinical Trial Activity: Robust clinical trial activity in the NSCLC drug market, focusing on novel therapeutic agents, combination therapies, and treatment modalities such as immunotherapy and targeted therapy combinations, stimulates innovation, fosters competition, and drives market growth.
  • Emerging Biologic Therapies: The emergence of biologic therapies, including monoclonal antibodies and antibody-drug conjugates, offers new treatment options for NSCLC patients, targeting specific cellular pathways and tumor antigens to inhibit tumor growth and improve survival outcomes.
  • Expanding Access to Healthcare: Efforts to improve access to healthcare services, including cancer screening, diagnosis, and treatment, in emerging markets and underserved populations, contribute to increased patient awareness, diagnosis rates, and treatment initiation, supporting market growth for NSCLC drugs on a global scale.
  • Advancements in Early Detection and Diagnosis: Improvements in screening techniques, imaging modalities, and diagnostic tools facilitate early detection and diagnosis of NSCLC, allowing for timely intervention and improved patient outcomes. Enhanced diagnostic capabilities contribute to increased treatment efficacy and drive market growth by expanding the eligible patient population for therapeutic interventions.
  • Regulatory Approvals and Market Access: Regulatory approvals for new NSCLC drugs, along with favorable reimbursement policies and market access initiatives, play a crucial role in driving the market growth. Expedited approval processes, breakthrough designations, and accelerated pathways enable timely access to innovative therapies, fostering competition, innovation, and investment in the NSCLC drug market.

NSCLC Drug Market: Partnership and Acquisitions

  • In 2023, Novocure announced successful results from the LUNAR study, demonstrating that Tumor Treating Fields (TTFields) combined with standard therapies for stage 4 non-small cell lung cancer (NSCLC) met its primary endpoint. This outcome signifies a promising advancement in treatment options for patients who have progressed after platinum-based therapy.
  • In 2023, AbbVie achieved a significant milestone with the FDA approval of EPKINLYTM (epcoritamab-bysp), the first T-cell engaging bispecific antibody sanctioned for treating adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) and high-grade B-cell lymphoma (HGBL) who have received two or more lines of systemic therapies.

Report Scope

Feature of the Report Details
Market Size in 2024 USD 34,175.6 Million
Projected Market Size in 2033 USD 68,888.6 Million
Market Size in 2023 USD 31,614.8 Million
CAGR Growth Rate 8.1% CAGR
Base Year 2023
Forecast Period 2024-2033
Key Segment By Cancer Type, Application, Molecule Type, Drug Class, Treatment Type, Diagnosis, End User and Region
Report Coverage Revenue Estimation and Forecast, Company Profile, Competitive Landscape, Growth Factors and Recent Trends
Regional Scope North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America
Buying Options Request tailored purchasing options to fulfil your requirements for research.

NSCLC Drug Market: COVID-19 Analysis

The COVID-19 pandemic has had a significant impact on the Non-Small-Cell Lung Cancer Drug Market, with the industry experiencing both positive and negative effects. Here are some of the key impacts:

  • Disruption in Healthcare Services: COVID-19 led to disruptions in healthcare services, including delays in cancer screenings, diagnostic procedures, and treatment initiation for NSCLC patients. Reduced patient visits to healthcare facilities and prioritization of resources for COVID-19 management resulted in decreased diagnosis rates and treatment adherence.
  • Clinical Trial Delays: Many clinical trials investigating novel NSCLC drugs experienced delays or suspensions due to pandemic-related restrictions, site closures, and challenges in patient recruitment and retention. This interruption in research activities hindered new therapies’ development and regulatory approval, impacting the pipeline of innovative treatments for NSCLC.
  • Resumption of Healthcare Services: As the pandemic situation improves, healthcare facilities are gradually resuming elective procedures, cancer screenings, and treatment services for NSCLC patients. Implementing safety protocols, telemedicine options, and patient education programs facilitates the safe resumption of healthcare services and ensures continuity of care.
  • Emphasis on Early Detection and Diagnosis: Efforts to catch up on missed cancer screenings and promote awareness about the importance of early detection of NSCLC are underway. Campaigns encouraging individuals to undergo lung cancer screening and seek medical attention for symptoms aim to facilitate early diagnosis and improve treatment outcomes.
  • Investment in Telemedicine and Remote Monitoring: Telemedicine platforms and remote monitoring technologies continue to play a crucial role in delivering care to NSCLC patients. Integration of telehealth services into oncology practices enables remote consultations, follow-ups, and monitoring of treatment responses, ensuring continuity of care while minimizing patient exposure to COVID-19.
  • Research Continuity and Innovation: The resumption of clinical trials and research activities is vital for advancing NSCLC treatment options. Increased collaboration, funding support, and innovative trial designs (such as decentralized trials) accelerate novel therapies’ development, driving recovery and progress in the NSCLC drug market.

In conclusion, the COVID-19 pandemic has had a mixed impact on the Non-Small-Cell Lung Cancer Drug Market, with some challenges and opportunities arising from the pandemic.

Global Non-Small-Cell Lung Cancer Drug Market 2024–2033 (By Million)

List of the prominent players in the NSCLC Drug Market:

  • AstraZeneca PLC
  • Bristol Myers Squibb Company
  • Merck & Co. Inc.
  • Hoffmann-La Roche Ltd.
  • Pfizer Inc.
  • Novartis AG
  • Eli Lilly and Company
  • Boehringer Ingelheim International GmbH
  • Takeda Pharmaceutical Company Limited
  • AbbVie Inc.
  • GlaxoSmithKline plc
  • Johnson & Johnson
  • Sanofi S.A.
  • Celgene Corporation
  • Daiichi Sankyo Company Limited
  • Others

The NSCLC Drug Market is segmented as follows:

By Cancer Type

  • Non-Small Cell Lung Cancer
  • Metastatic Lung Cancer
  • Pulmonary Neuroendocrine Tumours
  • Mediastina Tumours
  • Mesothelioma
  • Chest Wall Tumours

By Application

  • Adenocarcinomas
  • Squamous Cell Carcinoma
  • Large Cell Carcinomas
  • Others

By Molecule Type

  • Small Molecules
  • Biologics

By Drug Class

  • Alkylating Agents
  • Antimetabolites
  • EGFR Inhibitors
  • Mitotic Inhibitors
  • Multi-kinase Inhibitors
  • Others

By Treatment Type

  • Chemotherapy
  • Radiation Therapy
  • Targeted Therapy
  • Immunotherapy
  • Others

By Diagnosis

  • CT scan
  • X-Rays
  • Sputum Cytology
  • Bronchoscopy
  • Laboratory Tests
  • Thoracoscopy
  • Others

By End User

  • Hospitals
  • Homecare
  • Specialty Clinics
  • Others

Regional Coverage:

North America

  • U.S.
  • Canada
  • Mexico
  • Rest of North America


  • Germany
  • France
  • U.K.
  • Russia
  • Italy
  • Spain
  • Netherlands
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • New Zealand
  • Australia
  • South Korea
  • Taiwan
  • Rest of Asia Pacific

The Middle East & Africa

  • Saudi Arabia
  • UAE
  • Egypt
  • Kuwait
  • South Africa
  • Rest of the Middle East & Africa

Latin America

  • Brazil
  • Argentina
  • Rest of Latin America