Global Deep Eutectic Solvents Market 2025 – 2034

Reports Description

As per the Deep Eutectic Solvents Market analysis conducted by the CMI team, the deep eutectic solvents market is expected to record a CAGR of 15.27% from 2025 to 2034. In 2025, the market size was USD204.77 Million. By 2034, the valuation is anticipated to reach USD 735.89 Million.

Overview

Deep eutectic solvents constitute a class of environmentally benign solvents that are formed out of mixing a hydrogen bond donor (HBD) and hydrogen bond acceptor (HBA). This mixture, in turn, results in a visible depression of the melting point. Such solvents are looked upon as cost-effective and sustainable alternatives to conventional organic solvents. They are drawing attention as one of the viable alternatives to ionic liquids and conventional organic solvents owing to their non-toxicity, low volatility, and biodegradability. As the manufacturing sector witnesses rising frequencies of regulatory pressures for minimizing use of hazardous substances (volatile organic compounds (VOCs) in particular), there is a notable shift in the direction of green solvents.

Novel formulations are getting developed for specified industrial needs like pharmaceutical processing, metal recovery, and energy storage. For instance, researchers associated with the National Natural Science Foundation of China did develop a new ultra-microporous carbon material that is doped with oxygen and nitrogen using DES-assisted hydrothermal carbonization (DES-HTC) and KOH activation of microalgae. The material has been reported to exhibit superlative CO₂ adsorption capacity, thereby pushing it toward commercialization.

Key Trends & Drivers

• Stern International Environmental Regulations

Environmental regulations such as REACH (registration, Evaluation, Authorization, and restriction of Chemicals) in the EU and the Toxic Substances Control Act (TSCA) in the U.S. are pushing the manufacturing sector toward more sustainable chemical alternatives. Along these lines, the EU’s REACH regulation does restrict 224 chemical substances, whereas RoHS puts a cap on 10 hazardous substances in electronics and electrical equipment (EEE). Such regulations do set stringent compliance benchmarks for importers and manufacturers.

Non-compliance has been reported in pricey application recalls (around USD 11 Million). Such regulations aim to lessen hazardous substances’ environmental impact by restricting usage of toxic chemicals in the production processes. DESs are gaining traction owing to their biodegradable, non-toxic properties. In verticals such as food processing, pharmaceuticals, and chemicals, DESs are looked upon as viable alternatives to the hazardous solvents, as they do provide a pathway for meeting compliance standards while maintaining the operational efficiency.

• Increase in Investments in R&D and Green Chemistry

The rising focus on green technologies is accelerating investments in R&D activities for various alternative solvents, inclusive of deep eutectic solvents (DES). Private and public stakeholders are visibly contributing to funding of initiatives pertaining to green chemistry. In other words, they are aiming toward the development of sustainable solutions minimizing industrial processes’ environmental impact. On these grounds, in the year 2024, UNESCO, under the Green Chemistry Projects Award, did provide a grant of close to USD 0.19 Million to scientists for R&D activities related to green chemistry solutions.

Collaborations amongst research institutes, universities, and chemical companies are driving progress in comprehending DESs’ fundamental properties and improving their performance in different chemical processes. Such initiatives do catalyze technological advancements, adding commercialization of DES, thereby making them more cost-effective and feasible for use in vertical manufacturing.

What’s trending in the Deep Eutectic Solvents Market?

Regulations do play a vital role in shaping the deep eutectic solvents market, as they do restrict usage of hazardous chemicals and volatile organic compounds (VOCs). Also, DESs can’t be classified as hazardous chemicals, which, in turn, simplifies their approval for industrial uses. As such, DES is increasingly being used in a wide spectrum of industries, right from cosmetics and pharmaceuticals to energy, metallurgy, and food processing.

Key Threats

• Compatibility with Existing Equipment and Infrastructure and Long-term Toxicological Data Gaps

Interaction of DES with seals, metals, and polymers used in conventional chemical equipment may result in fouling or degradation. The industries may be required to invest in novel compatibility testing methods and materials to enable seamless integration. Also, in spite of the fact that DESs are propagated as green solvents, comprehensible long-term studies regarding their bioaccumulation, ecotoxicity, and degradation pathways are still facing limitations. As such, a higher volume of data is needed for supporting regulatory approvals as well as safe usage in the sensitive applications.

Opportunities

The evolution of Natural Deep Eutectic Solvents (NaDES) (derived from biomolecules such as urea, sugars, and organic acids) is driving their use in cosmetics, pharmaceuticals, and food industries. Such solvents could thus be effectively used for extracting products in their natural form, thereby improving bioavailability while maintaining the eco-friendly processing.

DESs are turning out to be prime enablers with regard to sustainable metallurgy, particularly for selective leaching as well as recovery of cobalt, lithium, and rare earth elements from e-waste and spent batteries. Non-toxicity on their part, combined with the capacity of metal solubilization, does render them suitable for the closed-loop recovery systems.

DESs do offer tunable polarity, viscosity, and acid-base behavior, thereby rendering them promising candidates to capture CO₂ post-combustion. Their low regeneration energy and recyclability in comparison with aqueous amines are promulgating research in DESs applications.

Category Wise Insights

By Product

• Organic Salts + Metal Salts

Organic and metal salts could be combined in different ratios for creating DESs with a broad spectrum of properties inclusive of viscosity, melting point, and polarity. Such tunability allows for developing DESs customized to specified applications. DESs formed out of such salts are capable of dissolving a broad range of inorganic and organic compounds, inclusive of metal ions, thereby rendering them useful in several separation and extraction processes. Several organic and metal salts, especially hydrated choline chloride and metal halides, are readily available and relatively less expensive.

• Organic Salts + Metal Hydrates

Organic salts and metal hydrates offer a broader range of cost-effective and personalized solvents. They facilitate the creation of Type II DESs, which do combine hydrated metal halides with various organic salts such as choline chloride, thereby widening the applicability of these DESs in several industries. they are also biodegradable, thereby contributing to DESs’ green chemistry principles. This makes them feasible for applications wherein environmental impact is of deep concern, such as metal recovery and extraction processes.

• Organic Salts + Hydrogen Bond Donor

Organic salts and hydrogen bond donors help in creating solvents with improved performance and tunable properties for several applications. Such components determine the melting point, solubility, and viscosity for DESs. Organic molecules such as alcohols, carboxylic acids, or amides do donate hydrogen atoms for forming hydrogen bonds. DESs are capable of acting as solvents for various catalytic reactions, thereby making provision for a medium for reactions to take place.

• Metal Chlorides + Hydrogen Bond Donor

Metal chlorides and hydrogen bond donors let fine-tuning of the hydrogen bonding network within DES, which substantially impacts the properties such as conductivity, viscosity, and melting point. Metal chlorides can also introduce Lewis acidity to DES, thereby making them applicable for catalysis and the other reactions that need electron-withdrawing capacities.

By End-use

• Pharmaceuticals & Healthcare

DESs could be used as drug delivery systems for several routes inclusive of transdermal, nasal, and oral administration, thereby improving therapeutic effectiveness after drug absorption. For instance, DESs are being used for formulating anti-tuberculosis drugs, thereby increasing permeability and solubility and even lessening drug resistance. They are also reported to enhance delivery of huge biomolecules such as proteins, thereby offering a non-invasive alternative to the injections.

• Food & Beverages Processing

DESs are proving to be effective in the extraction of bioactive compounds such as polyphenols, antioxidants, and flavonoids from several food sources such as vegetables, fruits, and herbs. They are especially useful in the extraction of compounds sensitive to conventional solvents/heat, thereby ascertaining higher yields and preserving the desired compounds’ integrity. This is relevant during the production of nutraceuticals and functional foods, wherein the presence of bioactive compounds is important.

• Cosmetics & Personal Care

NaDES are able to effectively extract antioxidants and phenolic compounds from plants. Such solvents can stabilize and solubilize such compounds, thereby rendering them more bioavailable as well as effective in the cosmetic formulations. For instance, NaDES are being used for extracting anthocyanins from green tea and grapes, which could be incorporated into the cosmetic products. As DESs also act as stabilizing agents, manufacturers of cosmetics can create long-lasting and more stable products with a broader range of natural ingredients.

• Chemicals & Materials Industry

The chemicals & materials industry helps in synthesizing DES from several sustainable and renewable sources, thereby optimizing their performance for specified applications and creating new users in different fields such as catalysis, extraction, and materials science. Research is emphasizing fine-tuning DES properties such as viscosity, melting point, and solubility for improving their performance in several processes.

How are R&D Investments Impacting the Deep Eutectic Solvents Market?

Investments in R&D activities are bound to provide an ample number of opportunities for the growth of the global deep eutectic solvents market. Novel combinations of hydrogen bond acceptors and donors are being discovered on a continuous basis by scientists and incorporated by the market players, thereby aiming to design properties catering to a wider range of applications. The new end-users could thus be amongst those dealing with bioplastics, advanced materials, and renewable energy.

Report Scope

Regional Perspective

The deep eutectic solvents market is classified into North America, Europe, Asia Pacific, and LAMEA.

• North America

North America holds a significant deep eutectic solvents market share. This could be credited to the region’s strong emphasis on green chemistry, followed by stringent environmental regulations and advanced research infrastructure. The U.S. pharmaceutical and chemical industries are into active adoption of sustainable solvents. Also, academic institutions are at the forefront with regard to commercializing DESs through pilot projects. The government is also supportive of eco-friendly technologies coupled with rising awareness regarding VOC-related risks.

• Europe

The growth of the deep eutectic solvents market in Europe is reasoned with strong regulatory pressure on the part of the EU to have non-biodegradable and toxic solvents replaced under REACH regulations. Moreover, Europe was amongst the first ones to promote green chemistry through its Circular Economy Action Plan, which does encourage adopting sustainable processes in consumer and industrial applications. Industry-academic collaborations followed by programs such as Horizon Europe are accelerating research related to DES, particularly for food processing, recycling, and pharmaceutical applications. Germany rules the roost, with DES increasingly being adopted for specialty coatings, metal surface treatment, and battery chemistry.

• Asia Pacific

Asia Pacific holds more than 39% of the market share. Rise in emphasis on sustainable production, rapid industrialization, and increasing investments in pharmaceutical, food, and chemical sectors are accelerating the deep eutectic solvents market over here. DES is thus getting integrated into electrochemistry, metal extraction, and biomass processing. Plus, expanding the base of the manufacturing vertical coupled with supportive frameworks is making provisions for strong opportunities for the suppliers of DESs across the emerging economies in the Asia Pacific. China is increasingly using DES in metallurgy, mining, and battery production for reducing environmental impact ad improving processing efficiency.

• LAMEA

LAMEA is focusing on green chemistry and sustainability on a continual basis. It is thus making DESs a feasible option owing to their lower toxicity and biodegradability as compared to traditional solvents. As economies in LAMEA diversify, there is an increasing need for cost-effective and efficient solvents across verticals such as pharmaceuticals, chemicals, and agriculture.

Key Developments

The deep eutectic solvents market is witnessing a significant organic and inorganic expansion. Some of the key developments include –

• In June 2025, Mitsubishi Corporation announced that it had invested in DEScycle Ltd. (U.K.). This partnership is formed with the objective of developing a pilot plant using deep eutectic solvents for metal recovery in an eco-friendly manner.

• In April 2024, Arkema announced that it had completed the acquisition of ~78% of the stake in Proionic (a start-up specialized in the ionic liquids important for next-generation lithium-ion batteries, inclusive of flexible and solid types). The latter’s expertise with respect to ionic liquids’ synthesis with the former’s goal of developing safer, sustainable, and more efficient batteries.

Leading Players

The deep eutectic solvents market is highly competitive, with a large number of service providers globally. Some of the key players in the market include:

• Proionic GmbH
• Iolitec Ionic Liquids Technologies GmbH
• Merck KGaA
• Thermo Fisher Scientific Inc.
• BASF SE
• Abbott Laboratories
• Solvay S.A.
• The Chemours Company
• Sirrus Inc.
• Green Biologics Ltd.
• GFS Chemicals Inc.
• Yuncheng Chemphy Chemical Co. Ltd.
• Eutec Solutions
• Shenzhen Capchem Technology Co. Ltd.
• NanJing HPL Chemical Co. Ltd.
• Others

These firms apply numerous strategies to enter the market, including innovations, mergers and acquisitions, and collaboration. The deep eutectic market is shaped by the presence of diversified players that compete based on product innovation, vertical integration, and cost efficiency.

The Deep Eutectic Solvents Market is segmented as follows:

By Product

• Organic Salts + Metal Salts
• Organic Salts + Metal Hydrates
• Organic Salts + Hydrogen Bond Donor
• Metal Chlorides + Hydrogen Bond Donor

By End-use

• Pharmaceuticals & Healthcare
• Food & Beverages Processing
• Cosmetics & Personal Care
• Chemical & Materials Industry

Regional Coverage:

North America

• U.S.
• Canada
• Mexico
• Rest of North America

Europe

• Germany
• France
• U.K.
• Russia
• Italy
• Spain
• Netherlands
• Rest of Europe

Asia Pacific

• China
• Japan
• India
• New Zealand
• Australia
• South Korea
• Taiwan
• Rest of Asia Pacific

The Middle East & Africa

• Saudi Arabia
• UAE
• Egypt
• Kuwait
• South Africa
• Rest of the Middle East & Africa

Latin America

• Brazil
• Argentina
• Rest of Latin America